Transposon activity, local duplications and propagation of structural variants across haplotypes drive the evolution of the Drosophila S2 cell line

BACKGROUND: Immortalized cell lines are widely used model systems whose genomes are often highly rearranged and polyploid. However, their genome structure is seldom deciphered and is thus not accounted for during analyses. We therefore used linked short- and long-read sequencing to perform haplotype...

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Detalles Bibliográficos
Autores principales: Lewerentz, Jacob, Johansson, Anna-Mia, Larsson, Jan, Stenberg, Per
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991648/
https://www.ncbi.nlm.nih.gov/pubmed/35392795
http://dx.doi.org/10.1186/s12864-022-08472-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991648/
https://www.ncbi.nlm.nih.gov/pubmed/35392795
http://dx.doi.org/10.1186/s12864-022-08472-1

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