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C/EBP homologous protein promotes Sonic Hedgehog secretion from type II alveolar epithelial cells and activates Hedgehog signaling pathway of fibroblast in pulmonary fibrosis

BACKGROUND: Endoplasmic reticulum (ER) stress is involved in the pathological process of pulmonary fibrosis, including IPF. It affects a broad scope of cellular types during pulmonary fibrosis but the role in epithelial-mesenchymal crosstalk has not been fully defined. The present study aimed to inv...

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Detalles Bibliográficos
Autores principales: Yang, Xiaoyu, Sun, Wei, Jing, Xiaoyan, Zhang, Qian, Huang, Hui, Xu, Zuojun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991723/
https://www.ncbi.nlm.nih.gov/pubmed/35395850
http://dx.doi.org/10.1186/s12931-022-02012-x