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Microbial synthesis of 4-hydroxybenzoic acid from renewable feedstocks

4-Hydroxybenzoic acid (4HBA) and its esterified forms can be used as preservatives in the pharmaceutical and food industries. Here, we reported the establishment of a coenzyme-A (CoA) free multi-enzyme cascade in Escherichia coli to utilize biobased (L)-tyrosine for efficient synthesis of 4HBA. The...

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Detalles Bibliográficos
Autores principales: Chen, Yueyang, Chen, Yufen, Liu, Lijun, Zhang, Yang, Yuan, Jifeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991815/
https://www.ncbi.nlm.nih.gov/pubmed/35415641
http://dx.doi.org/10.1016/j.fochms.2021.100059