Multimarker synaptic protein cerebrospinal fluid panels reflect TDP-43 pathology and cognitive performance in a pathological cohort of frontotemporal lobar degeneration

BACKGROUND: Synapse degeneration is an early event in pathological frontotemporal lobar degeneration (FTLD). Consequently, a surrogate marker of synapse loss could be used to monitor early pathologic changes in patients with underlying FTLD. The aim of this study was to evaluate the relationship of...

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Detalles Bibliográficos
Autores principales: Cervantes González, Alba, Irwin, David J., Alcolea, Daniel, McMillan, Corey T., Chen-Plotkin, Alice, Wolk, David, Sirisi, Sònia, Dols-Icardo, Oriol, Querol-Vilaseca, Marta, Illán-Gala, Ignacio, Santos-Santos, Miguel Angel, Fortea, Juan, Lee, Edward B., Trojanowski, John Q., Grossman, Murray, Lleó, Alberto, Belbin, Olivia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991834/
https://www.ncbi.nlm.nih.gov/pubmed/35395770
http://dx.doi.org/10.1186/s13024-022-00534-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991834/
https://www.ncbi.nlm.nih.gov/pubmed/35395770
http://dx.doi.org/10.1186/s13024-022-00534-y

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