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Introducing Lipophilicity to (Polyhydroxyalkyl)thiazolidine Carboxylic Acids Via Acylation

[Image: see text] The therapeutic efficacy of bioactive compounds is related to their bioavailability. In turn, the bioavailability depends on the equilibrium between the hydrophilicity and the lipophilicity. 2(R,S)-(Polyhydroxyalkyl)thiazolidine-4(R) carboxylic acids (TCAs), obtained from the conde...

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Detalles Bibliográficos
Autores principales: Novo Fernández, Olalla, Oliveros, Diego, Canela Garayoa, Ramon, Balcells Fluvià, Mercè, Méndez Arteaga, Jonh J., Eras Joli, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991926/
https://www.ncbi.nlm.nih.gov/pubmed/35415335
http://dx.doi.org/10.1021/acsomega.1c07078