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Introducing Lipophilicity to (Polyhydroxyalkyl)thiazolidine Carboxylic Acids Via Acylation
[Image: see text] The therapeutic efficacy of bioactive compounds is related to their bioavailability. In turn, the bioavailability depends on the equilibrium between the hydrophilicity and the lipophilicity. 2(R,S)-(Polyhydroxyalkyl)thiazolidine-4(R) carboxylic acids (TCAs), obtained from the conde...
Autores principales: | Novo Fernández, Olalla, Oliveros, Diego, Canela Garayoa, Ramon, Balcells Fluvià, Mercè, Méndez Arteaga, Jonh J., Eras Joli, Jordi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical Society
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991926/ https://www.ncbi.nlm.nih.gov/pubmed/35415335 http://dx.doi.org/10.1021/acsomega.1c07078 |
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