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Regulation of heterologous subtilin production in Bacillus subtilis W168

BACKGROUND: Subtilin is a peptide antibiotic (lantibiotic) natively produced by Bacillus subtilis ATCC6633. It is encoded in a gene cluster spaBTCSIFEGRK (spa-locus) consisting of four transcriptional units: spaS (subtilin pre-peptide), spaBTC (modification and export), spaIFEG (immunity) and spaRK...

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Detalles Bibliográficos
Autores principales: Zhang, Qian, Kobras, Carolin M., Gebhard, Susanne, Mascher, Thorsten, Wolf, Diana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8991943/
https://www.ncbi.nlm.nih.gov/pubmed/35392905
http://dx.doi.org/10.1186/s12934-022-01782-9