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Converting Double-Stranded DNA-Encoded Libraries (DELs) to Single-Stranded Libraries for More Versatile Selections

[Image: see text] DNA-encoded library (DEL) is an efficient high-throughput screening technology platform in drug discovery and is also gaining momentum in academic research. Today, the majority of DELs are assembled and encoded with double-stranded DNA tags (dsDELs) and has been selected against nu...

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Detalles Bibliográficos
Autores principales: Gui, Yuhan, Wong, Clara Shania, Zhao, Guixian, Xie, Chao, Hou, Rui, Li, Yizhou, Li, Gang, Li, Xiaoyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992267/
https://www.ncbi.nlm.nih.gov/pubmed/35415338
http://dx.doi.org/10.1021/acsomega.2c01152