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Adjuvant role of a T-type calcium channel blocker, TTA-A2, in lung cancer treatment with paclitaxel

Aim: Chemoresistance is a prevalent issue in cancer treatment. Paclitaxel (PTX) is a microtubule-binding anticancer drug used in various cancer treatments. However, cancer cells often show chemoresistance against PTX with the help of P-glycoprotein (Pgp) - a drug efflux pump. It has also been observ...

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Detalles Bibliográficos
Autores principales: Kumari, Neema, Giri, Pravin Shankar, Rath, Subha Narayan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992437/
https://www.ncbi.nlm.nih.gov/pubmed/35582374
http://dx.doi.org/10.20517/cdr.2021.54