Caspase‐8 Variant G Regulates Rheumatoid Arthritis Fibroblast‐Like Synoviocyte Aggressive Behavior

OBJECTIVE: Fibroblast‐like synoviocytes (FLS) play a pivotal role in rheumatoid arthritis (RA) by contributing to synovial inflammation and progressive joint damage. An imprinted epigenetic state is associated with the FLS aggressive phenotype. We identified CASP8 (encoding for caspase‐8) as a diffe...

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Detalles Bibliográficos
Autores principales: Ansalone, Cecilia, Ainsworth, Richard I., Nygaard, Gyrid, Ai, Rizi, Prideaux, Edward B., Hammaker, Deepa, Perumal, Narayanan B., Weichert, Ken, Tung, Frances, Kodandapani, Lalitha, Sauder, J. Michael, Mertsching, Elisabeth C., Benschop, Robert J., Boyle, David L., Wang, Wei, Firestein, Gary S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley Periodicals, Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992463/
https://www.ncbi.nlm.nih.gov/pubmed/34963199
http://dx.doi.org/10.1002/acr2.11384

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992463/
https://www.ncbi.nlm.nih.gov/pubmed/34963199
http://dx.doi.org/10.1002/acr2.11384

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