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Development of a TCR beta repertoire assay for profiling liquid biopsies from NSCLC donors

Aim: The aim of this study was to demonstrate the utility of T-Cell receptor beta (TCRβ) sequencing as a robust method for assessing T-cell repertoire changes in donors with non-small cell lung cancer (NSCLC). We further demonstrated the use of the assay by monitoring repertoire modulation in a defi...

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Detalles Bibliográficos
Autores principales: Jackson, Leisa P., Tjoa, Benjamin A., Mellert, Hestia, Pestano, Gary A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992474/
https://www.ncbi.nlm.nih.gov/pubmed/35582444
http://dx.doi.org/10.20517/cdr.2020.07