RET kinase alterations in targeted cancer therapy

The rearranged during transfection (RET) gene encodes a protein tyrosine kinase. RET alterations by point mutations and gene fusions were found in diverse cancers. RET fusions allow abnormal expression and activation of the oncogenic kinase, whereas only a few of RET point mutations found in human c...

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Detalles Bibliográficos
Autores principales: Liu, Xuan, Hu, Xueqing, Shen, Tao, Li, Qi, Mooers, Blaine H. M., Wu, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992479/
https://www.ncbi.nlm.nih.gov/pubmed/35582449
http://dx.doi.org/10.20517/cdr.2020.15

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992479/
https://www.ncbi.nlm.nih.gov/pubmed/35582449
http://dx.doi.org/10.20517/cdr.2020.15

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