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Reversal of doxorubicin resistance in lung cancer cells by neferine is explained by nuclear factor erythroid-derived 2-like 2 mediated lung resistance protein down regulation

Aim: Development of multi drug resistance and dose limiting cardiotoxicity are hindering the use of Doxorubicin (Dox) in clinical settings. Augmented dox efflux induced by lung resistance protein (LRP) over expression has been related to multi drug resistance phenotype in various cancers. An alkaloi...

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Detalles Bibliográficos
Autores principales: Paramasivan, Poornima, Kumar, Jothi Dinesh, Baskaran, Rathinasamy, Weng, Ching Feng, Padma, Viswanadha Vijaya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992493/
https://www.ncbi.nlm.nih.gov/pubmed/35582448
http://dx.doi.org/10.20517/cdr.2019.115