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Regulation of ABCB1 activity by microRNA-200c and microRNA-203a in breast cancer cells: the quest for microRNAs’ involvement in cancer drug resistance

Aim: ABCB1 is a major player in cancer drug resistance. The purpose of this study was to functionally assess the regulation of ABCB1 activity in a doxorubicin-resistant breast cancer cell line by miR-200c and miR-203. Methods: Human breast carcinoma cell lines MCF-7 (Doxorubicin-sensitive and not ex...

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Detalles Bibliográficos
Autores principales: Armada, Ana, Gomes, Bruno Costa, Viveiros, Miguel, Rueff, José, Rodrigues, António Sebastião
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992503/
https://www.ncbi.nlm.nih.gov/pubmed/35582584
http://dx.doi.org/10.20517/cdr.2019.24