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Longitudinal monitoring for the emergence of epidermal growth factor C797S resistance mutations in non-small cell lung cancer using blood-based droplet digital PCR

Validation of assays for the C797S mutation as a biomarker for osimertinib resistance is promising in guiding treatment decision-making for multidrug resistant non-small cell lung cancer. A newly developed droplet digital PCR (ddPCR) assay was used to retrospectively evaluate the emergence of the C7...

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Detalles Bibliográficos
Autores principales: Bowling, Mark, Arastu, Hyder, Edwards, Victoria, Jackson, Leisa, Thurston, Scott, Reese, Jordan, Mellert, Hestia, Pestano, Gary, Walker, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992510/
https://www.ncbi.nlm.nih.gov/pubmed/35582570
http://dx.doi.org/10.20517/cdr.2019.53