Drug-adapted cancer cell lines as preclinical models of acquired resistance

Acquired resistance formation limits the efficacy of anti-cancer therapies. Acquired and intrinsic resistance differ conceptually. Acquired resistance is the consequence of directed evolution, whereas intrinsic resistance depends on the (stochastic) presence of pre-existing resistance mechanisms. Pr...

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Detalles Bibliográficos
Autores principales: Michaelis, Martin, Wass, Mark N., Cinatl, Jindrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2019
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992517/
https://www.ncbi.nlm.nih.gov/pubmed/35582596
http://dx.doi.org/10.20517/cdr.2019.005

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992517/
https://www.ncbi.nlm.nih.gov/pubmed/35582596
http://dx.doi.org/10.20517/cdr.2019.005

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