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Emerging consensus on the mechanism of polyspecific substrate recognition by the multidrug transporter P-glycoprotein
P-glycoprotein (P-gp or ABCB1) is a member of the broad family of ABC transporters. P-gp participates in the establishment of physiological barriers limiting cellular access of a large number of toxic compounds. It thus plays important roles in the pharmacokinetics of these compounds. Cancer cells a...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
OAE Publishing Inc.
2019
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992534/ https://www.ncbi.nlm.nih.gov/pubmed/35582581 http://dx.doi.org/10.20517/cdr.2019.22 |