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Involvement of SNX1 in regulating EGFR endocytosis in a gefitinib-resistant NSCLC cell lines

The drug gefitinib, a specific inhibitor of EGFR tyrosine kinase, has been shown to suppress the activation of EGFR signaling for survival and cell proliferation in non-small cell lung cancer cell lines. For many years, EGFR endocytosis has served as a model for investigating ligand-induced, recepto...

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Detalles Bibliográficos
Autores principales: Nishimura, Yukio, Itoh, Kazuyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: OAE Publishing Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992535/
https://www.ncbi.nlm.nih.gov/pubmed/35582586
http://dx.doi.org/10.20517/cdr.2019.15