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3,3’-Diindolylmethane and its derivatives: nature-inspired strategies tackling drug resistant tumors by regulation of signal transduction, transcription factors and microRNAs
Indoles of cruciferous vegetables are promising anti-tumor agents. Studies with indole-3-carbinol and its dimeric product, 3,3’-diindolylmethane (DIM), suggest that these compounds have the ability to deregulate multiple cellular signaling pathways that are essential for tumor growth and spread. The...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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OAE Publishing Inc.
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8992569/ https://www.ncbi.nlm.nih.gov/pubmed/35582221 http://dx.doi.org/10.20517/cdr.2020.53 |