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Hybrid Proteins with Short Conformational Epitopes of the Receptor-Binding Domain of SARS-CoV-2 Spike Protein Promote Production of Virus-Neutralizing Antibodies When Used for Immunization

Based on the previously developed approach, hybrid recombinant proteins containing short conformational epitopes (a.a. 144-153, 337-346, 414-425, 496-507) of the receptor-binding domain (RBD) of SARS-CoV-2 Spike protein (S protein) were synthesized in Escherichia coli cells as potential components o...

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Detalles Bibliográficos
Autores principales: Karyagina, Anna S., Gromov, Alexander V., Grunina, Tatyana M., Lyaschuk, Alexander M., Poponova, Maria S., Kleymenov, Denis A., Strukova, Natalia V., Generalova, Maria S., Ryazanova, Anna V., Galushkina, Zoya M., Dobrynina, Olga Yu., Bolshakova, Tatyana N., Sergeeva, Maria V., Romanovskaya-Romanko, Ekaterina A., Krasilnikov, Igor V., Subbotina, Marina E., Lunin, Vladimir G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Pleiades Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993036/
https://www.ncbi.nlm.nih.gov/pubmed/35527370
http://dx.doi.org/10.1134/S0006297922040022