Cargando…

Hybrid Proteins with Short Conformational Epitopes of the Receptor-Binding Domain of SARS-CoV-2 Spike Protein Promote Production of Virus-Neutralizing Antibodies When Used for Immunization

Based on the previously developed approach, hybrid recombinant proteins containing short conformational epitopes (a.a. 144-153, 337-346, 414-425, 496-507) of the receptor-binding domain (RBD) of SARS-CoV-2 Spike protein (S protein) were synthesized in Escherichia coli cells as potential components o...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karyagina, Anna S., Gromov, Alexander V., Grunina, Tatyana M., Lyaschuk, Alexander M., Poponova, Maria S., Kleymenov, Denis A., Strukova, Natalia V., Generalova, Maria S., Ryazanova, Anna V., Galushkina, Zoya M., Dobrynina, Olga Yu., Bolshakova, Tatyana N., Sergeeva, Maria V., Romanovskaya-Romanko, Ekaterina A., Krasilnikov, Igor V., Subbotina, Marina E., Lunin, Vladimir G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Pleiades Publishing 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993036/ https://www.ncbi.nlm.nih.gov/pubmed/35527370 http://dx.doi.org/10.1134/S0006297922040022

Ejemplares similares

Development of a Platform for Producing Recombinant Protein Components of Epitope Vaccines for the Prevention of COVID-19
por: Karyagina, Anna S., et al.
Publicado: (2021)

Fusion of Lysostaphin to an Albumin Binding Domain Prolongs Its Half-Life and Bactericidal Activity in the Systemic Circulation
por: Grishin, Alexander V., et al.
Publicado: (2019)

The Influence of Dimerization on the Pharmacokinetics and Activity of an Antibacterial Enzyme Lysostaphin
por: Grishin, Alexander V., et al.
Publicado: (2019)

Recombinant domains III of Tick-Borne Encephalitis Virus envelope protein in combination with dextran and CpGs induce immune response and partial protectiveness against TBE virus infection in mice
por: Ershova, Anna S., et al.
Publicado: (2016)

Antibacterial and Anti-Biofilm Properties of Diopside Powder Loaded with Lysostaphin
por: Kudinova, Alina, et al.
Publicado: (2023)

Biocompatibility and Physico-Chemical Properties of Highly Porous PLA/HA Scaffolds for Bone Reconstruction
por: Zimina, Anna, et al.
Publicado: (2020)

Design and Immunological Properties of the Novel Subunit Virus-like Vaccine against SARS-CoV-2
por: Krasilnikov, Igor V., et al.
Publicado: (2022)

A Simple Protocol for the Determination of Lysostaphin Enzymatic Activity
por: Grishin, Alexander V., et al.
Publicado: (2020)

Rapid Assessment of Neutralizing Antibodies Using Influenza Viruses with a Luciferase Reporter
por: Sergeeva, M. V., et al.
Publicado: (2022)

SARS-CoV-2 Subunit Virus-like Vaccine Demonstrates High Safety Profile and Protective Efficacy: Preclinical Study
por: Vakhrusheva, Anna V., et al.
Publicado: (2022)

Solitary restriction endonucleases in prokaryotic genomes
por: Ershova, Anna S., et al.
Publicado: (2012)

109 Problems and prospects of development of the subunit TB vaccine
por: Tkachuk, A.B., et al.
Publicado: (2014)

Physiological and Pathological Remodeling of Cerebral Microvessels
por: Tregub, Pavel P., et al.
Publicado: (2022)

Safety and Immunogenicity of Betuvax-CoV-2, an RBD-Fc-Based SARS-CoV-2 Recombinant Vaccine: Preliminary Results of the First-in-Human, Randomized, Double-Blind, Placebo-Controlled Phase I/II Clinical Trial
por: Kudriavtsev, Aleksandr V., et al.
Publicado: (2023)

Flexibility of the Linker between the Domains of DNA Methyltransferase SsoII Revealed by Small-Angle X-Ray Scattering: Implications for Transcription Regulation in SsoII Restriction–Modification System
por: Konarev, Petr V., et al.
Publicado: (2014)

IFN-λ1 Displays Various Levels of Antiviral Activity In Vitro in a Select Panel of RNA Viruses
por: Plotnikova, Marina, et al.
Publicado: (2021)

IgGκ Signal Peptide Enhances the Efficacy of an Influenza Vector Vaccine against Respiratory Syncytial Virus Infection in Mice
por: Pulkina, Anastasia, et al.
Publicado: (2023)

A Protein Aggregation Based Test for Screening of the Agents Affecting Thermostability of Proteins
por: Eronina, Tatyana, et al.
Publicado: (2011)

Longitudinal Analysis of Neuraminidase and Hemagglutinin Antibodies to Influenza A Viruses after Immunization with Seasonal Inactivated Influenza Vaccines
por: Sergeeva, Mariia V., et al.
Publicado: (2023)

From Agonist to Antagonist: Modulation of the Physiological Action of Angiotensins by Protein Conjugation—Hemodynamics and Behavior
por: Zamolodchikova, Tatyana S., et al.
Publicado: (2021)

Enhancement of the Local CD8(+) T-Cellular Immune Response to Mycobacterium tuberculosis in BCG-Primed Mice after Intranasal Administration of Influenza Vector Vaccine Carrying TB10.4 and HspX Antigens
por: Vasilyev, Kirill, et al.
Publicado: (2021)

NPIDB: nucleic acid—protein interaction database
por: Kirsanov, Dmitry D., et al.
Publicado: (2013)

Scaffolding proteins in G-protein signaling
por: Andreeva, Alexandra V, et al.
Publicado: (2007)

White matter hyperintensity in different migraine subtypes
por: Dobrynina, L. A., et al.
Publicado: (2021)

Mucosal Influenza Vector Vaccine Carrying TB10.4 and HspX Antigens Provides Protection against Mycobacterium tuberculosis in Mice and Guinea Pigs
por: Sergeeva, Mariia, et al.
Publicado: (2021)

Bursts of amino acid replacements in protein evolution
por: Stolyarova, Anastasia V., et al.
Publicado: (2019)

VH3-53/66-Class RBD-Specific Human Monoclonal Antibody iB20 Displays Cross-Neutralizing Activity against Emerging SARS-CoV-2 Lineages
por: Kulemzin, Sergey V., et al.
Publicado: (2022)

Protective Effect of PBCA Nanoparticles Loaded with Thymulin Against the Relapsing-Remitting Form of Experimental Autoimmune Encephalomyelitis in Mice
por: Lunin, Sergey M., et al.
Publicado: (2019)

Cell Senescence and Central Regulators of Immune Response
por: Lunin, Sergey M., et al.
Publicado: (2022)

Pilot data of serum proteins from children with autism spectrum disorders
por: Kaysheva, Anna L., et al.
Publicado: (2019)

Peculiarities of the Regulation of Gene Expression in the Ecl18kI Restriction–Modification System
por: Burenina, O. Yu., et al.
Publicado: (2013)

Verification of a Novel Approach to Predicting Effects of Antibiotic Combinations: In Vitro Dynamic Model Study with Daptomycin and Gentamicin against Staphylococcus aureus
por: Golikova, Maria V., et al.
Publicado: (2020)

MPC-Based Prediction of Anti-Mutant Effectiveness of Antibiotic Combinations: In Vitro Model Study with Daptomycin and Gentamicin against Staphylococcus aureus
por: Golikova, Maria V., et al.
Publicado: (2021)

Structural and Immunoreactivity Properties of the SARS-CoV-2 Spike Protein upon the Development of an Inactivated Vaccine
por: Kordyukova, Larisa V., et al.
Publicado: (2023)

SECRET domain of variola virus CrmB protein can be a member of poxviral type II chemokine-binding proteins family
por: Antonets, Denis V, et al.
Publicado: (2010)

Phylogenetic analysis of Bacillus anthracis strains from Western Siberia reveals a new genetic cluster in the global population of the species
por: Pisarenko, Sergey V., et al.
Publicado: (2019)

Proteomic Screening for Amyloid Proteins
por: Nizhnikov, Anton A., et al.
Publicado: (2014)

Simulated vertical electric field data: An estimation from an improved coupling model for the lithosphere-atmosphere-ionosphere system
por: Prokhorov, Boris E., et al.
Publicado: (2019)

The Role of Intravesicular Proteins and the Protein Corona of Extracellular Vesicles in the Development of Drug-Induced Polyneuropathy
por: Yunusova, Natalia V., et al.
Publicado: (2023)

Transferability and Polymorphism of SSR Markers Located in Flavonoid Pathway Genes in Fragaria and Rubus Species
por: Lebedev, Vadim G., et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_p0416o2a2gls9ki6j3nnnaaeh0