Lower polyunsaturated fatty acid levels and FADS2 expression in adult compared to neonatal keratinocytes are associated with FADS2 promotor hypermethylation

Keratinocytes produce lipids that are critical for the skin barrier, however, little is known about the impact of age on fatty acid (FA) biosynthesis in these cells. We have examined the relationship between keratinocyte FA composition, lipid biosynthetic gene expression, gene promoter methylation a...

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Detalles Bibliográficos
Autores principales: Pararasa, C., Messenger, D.J., Barrett, K.E., Hyliands, D., Talbot, D., Fowler, M.I., Kawatra, T., Gunn, D.A., Lim, F.L., Wainwright, L.J., Jenkins, G., Griffiths, H.R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993048/
https://www.ncbi.nlm.nih.gov/pubmed/35219001
http://dx.doi.org/10.1016/j.bbrc.2022.02.055

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993048/
https://www.ncbi.nlm.nih.gov/pubmed/35219001
http://dx.doi.org/10.1016/j.bbrc.2022.02.055

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