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Enhanced anti-angiogenetic effect of transferrin receptor-mediated delivery of VEGF-trap in a glioblastoma mouse model

Glioblastoma (GBM) is a common and aggressive brain cancer that accounts for 60% of adult brain tumors. Anti-angiogenesis therapy is an attractive option due to the high vasculature density of GBM. However, the best-known anti-angiogenic therapeutics, bevacizumab, and aflibercept, have failed to sho...

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Detalles Bibliográficos
Autores principales: Zhao, Peng, Anami, Yasuaki, Gao, Peng, Fan, Xuejun, Li, Leike, Tsuchikama, Kyoji, Zhang, Ningyan, an, Zhiqiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993059/
https://www.ncbi.nlm.nih.gov/pubmed/35388745
http://dx.doi.org/10.1080/19420862.2022.2057269