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Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors

Adoptive cell therapy (ACT) has proven to be highly effective in treating blood cancers, but traditional approaches to ACT are poorly effective in treating solid tumors observed clinically. Novel delivery methods for therapeutic cells have shown promise for treatment of solid tumors when compared wi...

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Detalles Bibliográficos
Autores principales: Grosskopf, Abigail K., Labanieh, Louai, Klysz, Dorota D., Roth, Gillie A., Xu, Peng, Adebowale, Omokolade, Gale, Emily C., Jons, Carolyn K., Klich, John H., Yan, Jerry, Maikawa, Caitlin L., Correa, Santiago, Ou, Ben S., d’Aquino, Andrea I., Cochran, Jennifer R., Chaudhuri, Ovijit, Mackall, Crystal L., Appel, Eric A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993118/
https://www.ncbi.nlm.nih.gov/pubmed/35394838
http://dx.doi.org/10.1126/sciadv.abn8264