Cargando…
Delivery of CAR-T cells in a transient injectable stimulatory hydrogel niche improves treatment of solid tumors
Adoptive cell therapy (ACT) has proven to be highly effective in treating blood cancers, but traditional approaches to ACT are poorly effective in treating solid tumors observed clinically. Novel delivery methods for therapeutic cells have shown promise for treatment of solid tumors when compared wi...
Autores principales: | Grosskopf, Abigail K., Labanieh, Louai, Klysz, Dorota D., Roth, Gillie A., Xu, Peng, Adebowale, Omokolade, Gale, Emily C., Jons, Carolyn K., Klich, John H., Yan, Jerry, Maikawa, Caitlin L., Correa, Santiago, Ou, Ben S., d’Aquino, Andrea I., Cochran, Jennifer R., Chaudhuri, Ovijit, Mackall, Crystal L., Appel, Eric A. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993118/ https://www.ncbi.nlm.nih.gov/pubmed/35394838 http://dx.doi.org/10.1126/sciadv.abn8264 |
Ejemplares similares
-
Inosine Induces Stemness Features in CAR T cells and Enhances Potency
por: Klysz, Dorota D., et al.
Publicado: (2023) -
Potent antitumor efficacy of anti-GD2 CAR T-cells in H3K27M+ diffuse midline gliomas
por: Mount, Christopher W., et al.
Publicado: (2018) -
Hydrogel‐Based Slow Release of a Receptor‐Binding Domain Subunit Vaccine Elicits Neutralizing Antibody Responses Against SARS‐CoV‐2
por: Gale, Emily C., et al.
Publicado: (2021) -
Consistent tumorigenesis with self-assembled hydrogels enables high-powered murine cancer studies
por: Grosskopf, Abigail K., et al.
Publicado: (2021) -
Nanoparticles Presenting Potent TLR7/8 Agonists Enhance
Anti-PD-L1 Immunotherapy in Cancer Treatment
por: Smith, Anton A. A., et al.
Publicado: (2020)