Reductive site-selective atypical C,Z-type/N2-C2 cleavage allows C-terminal protein amidation

Biomolecule environments can enhance chemistries with the potential to mediate and modulate self-modification (e.g., self-cleavage). While these enhanced modes are found in certain biomolecules (e.g., RNA ribozymes), it is more rare in proteins. Targeted proteolytic cleavage is vital to physiology,...

Descripción completa

Detalles Bibliográficos
Autores principales: Mollner, Tim A., Giltrap, Andrew M., Zeng, Yibo, Demyanenko, Yana, Buchanan, Charles, Oehlrich, Daniel, Baldwin, Andrew J., Anthony, Daniel C., Mohammed, Shabaz, Davis, Benjamin G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2022
Materias:
Physical and Materials Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993120/
https://www.ncbi.nlm.nih.gov/pubmed/35394836
http://dx.doi.org/10.1126/sciadv.abl8675

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993120/
https://www.ncbi.nlm.nih.gov/pubmed/35394836
http://dx.doi.org/10.1126/sciadv.abl8675

Ejemplares similares