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Reductive site-selective atypical C,Z-type/N2-C2 cleavage allows C-terminal protein amidation

Biomolecule environments can enhance chemistries with the potential to mediate and modulate self-modification (e.g., self-cleavage). While these enhanced modes are found in certain biomolecules (e.g., RNA ribozymes), it is more rare in proteins. Targeted proteolytic cleavage is vital to physiology,...

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Detalles Bibliográficos
Autores principales:	Mollner, Tim A., Giltrap, Andrew M., Zeng, Yibo, Demyanenko, Yana, Buchanan, Charles, Oehlrich, Daniel, Baldwin, Andrew J., Anthony, Daniel C., Mohammed, Shabaz, Davis, Benjamin G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Association for the Advancement of Science 2022
Materias:	Physical and Materials Sciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993120/ https://www.ncbi.nlm.nih.gov/pubmed/35394836 http://dx.doi.org/10.1126/sciadv.abl8675

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