Co-aggregation and secondary nucleation in the life cycle of human prolactin/galanin functional amyloids

Synergistic-aggregation and cross-seeding by two different proteins/peptides in the amyloid aggregation are well evident in various neurological disorders including Alzheimer’s disease. Here, we show co-storage of human Prolactin (PRL), which is associated with lactation in mammals, and neuropeptide...

Descripción completa

Detalles Bibliográficos
Autores principales: Chatterjee, Debdeep, Jacob, Reeba S, Ray, Soumik, Navalkar, Ambuja, Singh, Namrata, Sengupta, Shinjinee, Gadhe, Laxmikant, Kadu, Pradeep, Datta, Debalina, Paul, Ajoy, Arunima, Sakunthala, Mehra, Surabhi, Pindi, Chinmai, Kumar, Santosh, Singru, Praful, Senapati, Sanjib, Maji, Samir K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Biochemistry and Chemical Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993219/
https://www.ncbi.nlm.nih.gov/pubmed/35257659
http://dx.doi.org/10.7554/eLife.73835

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993219/
https://www.ncbi.nlm.nih.gov/pubmed/35257659
http://dx.doi.org/10.7554/eLife.73835

Ejemplares similares