Synthesis of indole-based oxadiazoles and their interaction with bacterial peptidoglycan and SARS-CoV-2 main protease: In vitro, molecular docking and in silico ADME/Tox study

In the present study, Indole-based-oxadiazole (1A-17A) compounds were successfully synthesized. The structures of all synthesized compounds were fully characterized by different sophisticated spectroscopic techniques such 1H NMR, 13C NMR, and HREI-MS. Further, the synthesized compounds were explored...

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Detalles Bibliográficos
Autores principales: Ansari, Mohammad Azam, Taha, Muhammad, Uddin, Nizam, Rahim, Fazal, Jamal, Qazi Mohammad Sajid, Alomary, Mohammad N., Alshabrmi, Fahad M., Almatroudi, Ahmad, Atwah, Banan, Alhindi, Zain, Iqbal, Naveed, Khan, Khalid Mohammed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. Published by Elsevier B.V. on behalf of King Saud University. 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993490/
http://dx.doi.org/10.1016/j.jscs.2022.101474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993490/
http://dx.doi.org/10.1016/j.jscs.2022.101474

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