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Post-Translational Modifications of BRD4: Therapeutic Targets for Tumor

Bromodomain-containing protein 4 (BRD4), a member of the bromodomain and extraterminal (BET) family, is considered to be a major driver of cancer cell growth and a new target for cancer therapy. Over 30 targeted inhibitors currently in preclinical and clinical trials have significant inhibitory effe...

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Detalles Bibliográficos
Autores principales: Liu, Na, Ling, Rui, Tang, Xiang, Yu, Yunpeng, Zhou, Yuepeng, Chen, Deyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993501/
https://www.ncbi.nlm.nih.gov/pubmed/35402244
http://dx.doi.org/10.3389/fonc.2022.847701