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Effective targeting of breast cancer stem cells by combined inhibition of Sam68 and Rad51

Breast cancer (BC) is the second cause of cancer-related deceases in the worldwide female population. Despite the successful treatment advances, 25% of BC develops resistance to current therapeutic regimens, thereby remaining a major hurdle for patient management. Current therapies, targeting the mo...

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Detalles Bibliográficos
Autores principales: Turdo, Alice, Gaggianesi, Miriam, Di Franco, Simone, Veschi, Veronica, D’Accardo, Caterina, Porcelli, Gaetana, Lo Iacono, Melania, Pillitteri, Irene, Verona, Francesco, Militello, Gabriella, Zippo, Alessio, Poli, Vittoria, Fagnocchi, Luca, Beyes, Sven, Stella, Stefania, Lattanzio, Rossano, Faldetta, Naida, Lentini, Vincenzo L., Porcasi, Rossana, Pistone, Giuseppe, Bongiorno, Maria Rita, Stassi, Giorgio, De Maria, Ruggero, Todaro, Matilde
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993694/
https://www.ncbi.nlm.nih.gov/pubmed/35217791
http://dx.doi.org/10.1038/s41388-022-02239-4