Defibrotide Therapy for SARS-CoV-2 ARDS

BACKGROUND: SARS-CoV-2-related ARDS is associated with endothelial dysfunction and profound dysregulation of the thrombotic-fibrinolytic pathway. Defibrotide is a polyanionic compound with fibrinolytic, antithrombotic, and antiinflammatory properties. RESEARCH QUESTION: What is the safety and tolera...

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Detalles Bibliográficos
Autores principales: Frame, David, Scappaticci, Gianni B., Braun, Thomas M., Maliarik, Mary, Sisson, Thomas H., Pipe, Steven W., Lawrence, Daniel A., Richardson, Paul G., Holinstat, Michael, Hyzy, Robert C., Kaul, Daniel R., Gregg, Kevin S., Lama, Vibha N., Yanik, Gregory A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American College of Chest Physicians 2022
Materias:
Critical Care: Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993696/
https://www.ncbi.nlm.nih.gov/pubmed/35413279
http://dx.doi.org/10.1016/j.chest.2022.03.046

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993696/
https://www.ncbi.nlm.nih.gov/pubmed/35413279
http://dx.doi.org/10.1016/j.chest.2022.03.046

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