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Skeletal muscle phenotyping of Hippo gene-mutated mice reveals that Lats1 deletion increases the percentage of type I muscle fibers

The Hippo signal transduction network regulates transcription through Yap/Taz-Tead1-4 in many tissues including skeletal muscle. Whilst transgenic mice have been generated for many Hippo genes, the resultant skeletal muscle phenotypes were not always characterized. Here, we aimed to phenotype the hi...

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Detalles Bibliográficos
Autores principales: Nezhad, Fakhreddin Yaghoob, Riermeier, Annett, Schönfelder, Martin, Becker, Lore, de Angelis, Martin Hrabĕ, Wackerhage, Henning
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993742/
https://www.ncbi.nlm.nih.gov/pubmed/34984591
http://dx.doi.org/10.1007/s11248-021-00293-4