TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis

Mitochondria are essential for cardiac myocyte function, but damaged mitochondria trigger cardiac myocyte death. Although mitophagy, a lysosomal degradative pathway to remove damaged mitochondria, is robustly active in cardiac myocytes in the unstressed heart, its mechanisms and physiological role r...

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Detalles Bibliográficos
Autores principales: Ma, Xiucui, Rawnsley, David R., Kovacs, Attila, Islam, Moydul, Murphy, John T., Zhao, Chen, Kumari, Minu, Foroughi, Layla, Liu, Haiyan, Qi, Kevin, Diwan, Aaradhya, Hyrc, Krzysztof, Evans, Sarah, Satoh, Takashi, French, Brent A., Margulies, Kenneth B., Javaheri, Ali, Razani, Babak, Mann, Douglas L., Mani, Kartik, Diwan, Abhinav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Preclinical Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993766/
https://www.ncbi.nlm.nih.gov/pubmed/35411325
http://dx.doi.org/10.1016/j.jacbts.2021.12.002

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993766/
https://www.ncbi.nlm.nih.gov/pubmed/35411325
http://dx.doi.org/10.1016/j.jacbts.2021.12.002

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