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TRAF2, an Innate Immune Sensor, Reciprocally Regulates Mitophagy and Inflammation to Maintain Cardiac Myocyte Homeostasis
Mitochondria are essential for cardiac myocyte function, but damaged mitochondria trigger cardiac myocyte death. Although mitophagy, a lysosomal degradative pathway to remove damaged mitochondria, is robustly active in cardiac myocytes in the unstressed heart, its mechanisms and physiological role r...
Autores principales: | Ma, Xiucui, Rawnsley, David R., Kovacs, Attila, Islam, Moydul, Murphy, John T., Zhao, Chen, Kumari, Minu, Foroughi, Layla, Liu, Haiyan, Qi, Kevin, Diwan, Aaradhya, Hyrc, Krzysztof, Evans, Sarah, Satoh, Takashi, French, Brent A., Margulies, Kenneth B., Javaheri, Ali, Razani, Babak, Mann, Douglas L., Mani, Kartik, Diwan, Abhinav |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993766/ https://www.ncbi.nlm.nih.gov/pubmed/35411325 http://dx.doi.org/10.1016/j.jacbts.2021.12.002 |
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