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Hyperadhesive von Willebrand Factor Promotes Extracellular Vesicle-Induced Angiogenesis: Implication for LVAD-Induced Bleeding

Bleeding associated with left ventricular assist device (LVAD) implantation has been attributed to the loss of large von Willebrand factor (VWF) multimers to excessive cleavage by ADAMTS-13, but this mechanism is not fully supported by the current evidence. We analyzed VWF reactivity in longitudinal...

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Detalles Bibliográficos
Autores principales: Yang, Mengchen, Houck, Katie L., Dong, Xinlong, Hernandez, Maria, Wang, Yi, Nathan, Sriram S., Wu, Xiaoping, Afshar-Kharghan, Vahid, Fu, Xiaoyun, Cruz, Miguel A., Zhang, Jianning, Nascimbene, Angelo, Dong, Jing-fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993768/
https://www.ncbi.nlm.nih.gov/pubmed/35411318
http://dx.doi.org/10.1016/j.jacbts.2021.12.005