Loss of luminal carbonic anhydrase XIV results in decreased biliary bicarbonate output, liver fibrosis, and cholangiocyte proliferation in mice

Carbonic anhydrase XIV (Car14) is highly expressed in the hepatocyte, with predominance in the canalicular membrane and its active site in the extracellular milieu. The aim of this study is to determine the physiological relevance of Car14 for biliary fluid and acid/base output, as well as its role...

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Detalles Bibliográficos
Autores principales: Zhou, Zhenzhen, Qian, Jiajie, Kini, Archana, Riederer, Brigitte, Römermann, Dorothee, Gros, Gerolf, Seidler, Ursula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Organ Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993780/
https://www.ncbi.nlm.nih.gov/pubmed/35119514
http://dx.doi.org/10.1007/s00424-021-02659-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993780/
https://www.ncbi.nlm.nih.gov/pubmed/35119514
http://dx.doi.org/10.1007/s00424-021-02659-3

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