Cargando…

Specific inflammatory osteoclast precursors induced during chronic inflammation give rise to highly active osteoclasts associated with inflammatory bone loss

Elevated osteoclast (OC) activity is a major contributor to inflammatory bone loss (IBL) during chronic inflammatory diseases. However, the specific OC precursors (OCPs) responding to inflammatory cues and the underlying mechanisms leading to IBL are poorly understood. We identified two distinct OCP...

Descripción completa

Detalles Bibliográficos
Autores principales: Meirow, Yaron, Jovanovic, Milena, Zur, Yuval, Habib, Juliana, Colombo, Daniele Filippo, Twaik, Nira, Ashkenazi-Preiser, Hadas, Ben-Meir, Kerem, Mikula, Ivan, Reuven, Or, Kariv, Guy, Daniel, Leonor, Baraghithy, Saja, Klein, Yehuda, Krijgsveld, Jeroen, Levaot, Noam, Baniyash, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993801/
https://www.ncbi.nlm.nih.gov/pubmed/35396510
http://dx.doi.org/10.1038/s41413-022-00206-z