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Dopamine receptor 1 expressing B cells exert a proinflammatory role in female patients with rheumatoid arthritis

Rheumatoid arthritis (RA) is a chronic rheumatic disease with a clear sex-bias. Recent data indicated a role for dopamine in RA pathogenesis, while dopaminergic pathways can be modulated by estrogens. As defined mechanism of action of dopamine on B cell function in RA are unclear, we aimed to elucid...

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Detalles Bibliográficos
Autores principales: Wieber, Karolin, Fleige, Leonie, Tsiami, Styliani, Reinders, Jörg, Braun, Jürgen, Baraliakos, Xenofon, Capellino, Silvia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993840/
https://www.ncbi.nlm.nih.gov/pubmed/35396380
http://dx.doi.org/10.1038/s41598-022-09891-6