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Angiotensin II related glial cell activation and necroptosis of retinal ganglion cells after systemic hypotension in glaucoma
The purpose of this study was to design an animal model mimicking glaucoma with hemodynamic instability and to identify involvement of angiotensin II (AngII) and associated changes of the retina. Systemic hypotension was induced in Sprague–Dawley rats by oral hydrochlorothiazide administration. Rats...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993868/ https://www.ncbi.nlm.nih.gov/pubmed/35396550 http://dx.doi.org/10.1038/s41419-022-04762-4 |