Pyroptosis executor gasdermin D plays a key role in scleroderma and bleomycin-induced skin fibrosis

The NLRP3 inflammasome and IL-1β are essential for scleroderma pathogenesis. Nevertheless, the role of pyroptosis executor gasdermin D(GSDMD), which is a downstream molecule of NLRP3 and is required for IL-1β release in some situations, has not yet been well elucidated in scleroderma. Here, we found...

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Huan, Shi, Yanqiang, Liu, Huiting, Lin, Feiyan, Qiu, Biying, Feng, Qinglan, Wang, Yu, Yang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993883/
https://www.ncbi.nlm.nih.gov/pubmed/35396386
http://dx.doi.org/10.1038/s41420-022-00970-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993883/
https://www.ncbi.nlm.nih.gov/pubmed/35396386
http://dx.doi.org/10.1038/s41420-022-00970-1

Ejemplares similares