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Targeting matrix metallopeptidase 2 by hydroxyurea selectively kills acute myeloid mixed-lineage leukemia

Oncogene-induced tumorigenesis results in the variation of epigenetic modifications, and in addition to promoting cell immortalization, cancer cells undergo more intense cellular stress than normal cells and depend on other support genes for survival. Chromosomal translocations of mixed-lineage leuk...

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Detalles Bibliográficos
Autores principales: Wang, Ruiheng, Xie, Shufeng, Zhu, Shouhai, Sun, Yong, Shi, Bowen, Li, Dan, Kang, Ting, Wang, Yuanli, Xu, Zhenshu, Liu, Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993889/
https://www.ncbi.nlm.nih.gov/pubmed/35396375
http://dx.doi.org/10.1038/s41420-022-00989-4