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Suppression of histone deacetylase 1 by JSL-1 attenuates the progression and metastasis of cholangiocarcinoma via the TPX2/Snail axis

Histone deacetylases (HDACs) are entwined with the pathogenesis of various cancers and potentially serve as promising therapeutic targets. Herein, we intend to explore the potential role of HDAC1 inhibitor (JSL-1) in the tumorigenesis and metastasis of cholangiocarcinoma (CC) and to highlight the mo...

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Detalles Bibliográficos
Autores principales: Xu, Lu, Yang, Weizhong, Che, Jinhui, Li, Deqiang, Wang, Haihong, Li, Yunjiu, Zhou, Wuyuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8993895/
https://www.ncbi.nlm.nih.gov/pubmed/35395834
http://dx.doi.org/10.1038/s41419-022-04571-9