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Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals

Chromosome segregation in mammals relies on the maturation of a thick bundle of kinetochore-attached microtubules known as k-fiber. How k-fibers mature from initial kinetochore microtubule attachments remains a fundamental question. By combining molecular perturbations and phenotypic analyses in Ind...

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Detalles Bibliográficos
Autores principales: Almeida, Ana C., Soares-de-Oliveira, Joana, Drpic, Danica, Cheeseman, Liam P., Damas, Joana, Lewin, Harris A., Larkin, Denis M., Aguiar, Paulo, Pereira, António J., Maiato, Helder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994134/
https://www.ncbi.nlm.nih.gov/pubmed/35385739
http://dx.doi.org/10.1016/j.celrep.2022.110610