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Augmin-dependent microtubule self-organization drives kinetochore fiber maturation in mammals
Chromosome segregation in mammals relies on the maturation of a thick bundle of kinetochore-attached microtubules known as k-fiber. How k-fibers mature from initial kinetochore microtubule attachments remains a fundamental question. By combining molecular perturbations and phenotypic analyses in Ind...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cell Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994134/ https://www.ncbi.nlm.nih.gov/pubmed/35385739 http://dx.doi.org/10.1016/j.celrep.2022.110610 |