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Emergence of the primordial pre-60S from the 90S pre-ribosome

Synthesis of ribosomes begins in the nucleolus with formation of the 90S pre-ribosome, during which the pre-40S and pre-60S pathways diverge by pre-rRNA cleavage. However, it remains unclear how, after this uncoupling, the earliest pre-60S subunit continues to develop. Here, we reveal a large-subuni...

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Detalles Bibliográficos
Autores principales: Ismail, Sherif, Flemming, Dirk, Thoms, Matthias, Gomes-Filho, José Vicente, Randau, Lennart, Beckmann, Roland, Hurt, Ed
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994135/
https://www.ncbi.nlm.nih.gov/pubmed/35385737
http://dx.doi.org/10.1016/j.celrep.2022.110640