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The role of TBK1 in cancer pathogenesis and anticancer immunity

The TANK-binding kinase 1 (TBK1) is a serine/threonine kinase belonging to the non-canonical inhibitor of nuclear factor-κB (IκB) kinase (IKK) family. TBK1 can be activated by pathogen-associated molecular patterns (PAMPs), inflammatory cytokines, and oncogenic kinases, including activated K-RAS/N-R...

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Detalles Bibliográficos
Autores principales: Runde, Austin P., Mack, Ryan, S.J., Peter Breslin, Zhang, Jiwang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994244/
https://www.ncbi.nlm.nih.gov/pubmed/35395857
http://dx.doi.org/10.1186/s13046-022-02352-y