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TGF-β induced reprogramming and drug resistance in triple-negative breast cells

BACKGROUND: The development of drug resistance remains to be a major cause of therapeutic failure in breast cancer patients. How drug-sensitive cells first evade drug inhibition to proliferate remains to be fully investigated. METHODS: Here we characterized the early transcriptional evolution in res...

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Detalles Bibliográficos
Autores principales: Wu, Guoyu, Li, Yuchao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994282/
https://www.ncbi.nlm.nih.gov/pubmed/35395809
http://dx.doi.org/10.1186/s40360-022-00561-x