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Dose–response relationship of pulmonary disorders by inhalation exposure to cross-linked water-soluble acrylic acid polymers in F344 rats

BACKGROUND: In Japan, six workers handling cross-linked water-soluble acrylic acid polymer (CWAAP) at a chemical plant suffered from lung diseases, including fibrosis, interstitial pneumonia, emphysema, and pneumothorax. We recently demonstrated that inhalation of CWAAP-A, one type of CWAAP, causes...

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Detalles Bibliográficos
Autores principales: Takeda, Tomoki, Yamano, Shotaro, Goto, Yuko, Hirai, Shigeyuki, Furukawa, Yusuke, Kikuchi, Yoshinori, Misumi, Kyohei, Suzuki, Masaaki, Takanobu, Kenji, Senoh, Hideki, Saito, Misae, Kondo, Hitomi, Daghlian, George, Hong, Young-Kwon, Yoshimatsu, Yasuhiro, Hirashima, Masanori, Kobashi, Yoichiro, Okamoto, Kenzo, Kishimoto, Takumi, Umeda, Yumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994297/
https://www.ncbi.nlm.nih.gov/pubmed/35395797
http://dx.doi.org/10.1186/s12989-022-00468-9