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Patient-Derived Anti-NMDAR Antibody Disinhibits Cortical Neuronal Networks through Dysfunction of Inhibitory Neuron Output

Anti-NMDA receptor (NMDAR) encephalitis is a severe neuropsychiatric disorder associated with autoantibodies against NMDARs, which cause a variety of symptoms from prominent psychiatric and cognitive manifestations to seizures and autonomic instability. Previous studies mainly focused on hippocampal...

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Detalles Bibliográficos
Autores principales: Andrzejak, Ewa, Rabinovitch, Eshed, Kreye, Jakob, Prüss, Harald, Rosenmund, Christian, Ziv, Noam E., Garner, Craig C., Ackermann, Frauke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994542/
https://www.ncbi.nlm.nih.gov/pubmed/35241491
http://dx.doi.org/10.1523/JNEUROSCI.1689-21.2022