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Effects of chameleon dispense-to-plunge speed on particle concentration, complex formation, and final resolution: A case study using the Neisseria gonorrhoeae ribonucleotide reductase inactive complex

Ribonucleotide reductase (RNR) is an essential enzyme that converts ribonucleotides to deoxyribonucleotides and is a promising antibiotic target, but few RNRs have been structurally characterized. We present the use of the chameleon, a commercially-available piezoelectric cryogenic electron microsco...

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Detalles Bibliográficos
Autores principales: Levitz, Talya S., Brignole, Edward J., Fong, Ivan, Darrow, Michele C., Drennan, Catherine L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8994553/
https://www.ncbi.nlm.nih.gov/pubmed/34906669
http://dx.doi.org/10.1016/j.jsb.2021.107825